Ghent University (UGent) - VIB - Belgium
Center for Inflammation Research
Unit of Molecular Signal Transduction in Inflammation (UMSTI)
The UMSTI headed by Prof. Rudi Beyaert has a job opening for a postdoctoral scientist to interrogate inflammatory bowel disease (IBD)-relevant functions of GWAS-identified candidate genes.
Research context + job description
The UMSTI (https://www.irc.ugent.be/rbe) studies the molecular and cellular mechanisms that control inflammation and immunity. In the frame of the EOS (Excellence of Science) funding programme we have recently initiated the BRIDGE project (Taking IBD Genes from GWAS to Function to Drug Target). BRIDGE brings together scientists from 4 different Belgian universities and 1 US lab with complementary expertise in genomics, immunology, cell biology, and clinical gastroenterology to jointly develop a pipeline to systematically interrogate IBD-relevant functions of GWAS-identified candidate genes relevant to disease activation and recurrence.
The successful candidate will focus on the functional characterization of selected IBD candidate genes in enteroendocrine cells, Paneth cells, and/or T cells, using human primary cells and cell lines, gut organoids, and mouse models. You will make a significant input into determining the direction of the project and identify, develop, modify and apply the necessary techniques to achieve the goals of the project. You will also supervise a Ph.D. student.
What do we offer?
- 3 years contract (extendable); flexible starting date; competitive salary and benefits
- a very supporting international research team sharing a passion for science
- access to cutting-edge infrastructure and core facilities
- become part of a multidisciplinary network of top-notch laboratories focusing on IBD
- personal career assistance and a seat waiting in high-level training courses
- a vibrant UGent (https://www.ugent.be/en/ghentuniv) and VIB (https://vib.be/ten-good-reasons-work-vib) international research environment located in Ghent, Europe’s best-kept secret
- Ph.D. obtained in the last 5 years in a relevant discipline
- a strong passion for science and curiosity-driven research
- ability to work independently and in a team
- good writing and communication skills in English
- excellent track record (at least one first-author research publication in a Q1-ranking journal)
- solid background in immunology, in particular in T cell biology or epithelial barrier immunity
- expertise with mouse models and/or mouse engineering
Complete the online application procedure and include (1) CV, (2) a letter describing your past research activities and fascination for the topic and Beyaert lab, (3) contact details of 2 referees.
The vacancy will stay open until a suitable candidate has been found.
Applications by email will not be considered.