We are interested in mechanisms of how immune system imbalance leads to human disease. Our group focuses on the role of specific immune cells in this process, in particular on the interplay of anti-inflammatory CD4+ regulatory T cells and pro-inflammatory CD4+ effector T cells. Here, our major interest lies in the understanding of the processes that lead to autoimmune diseases like multiple sclerosis or are related to metabolic- and cardiovascular diseases and cancer.
To study these processes, we use a translational approach, combining the analysis of human samples and the use of experimental model systems by various immunological and molecular biology state-of-the-art techniques.
Currently we focus on the following topics:
- Environmental factors (e.g. nutrition, microbiota) influencing the immune cell balance and disease (for overview: Jörg et al., Cell Mol Life Sci. 2016, Matveeva et al., Ann N Y Acad Sci. 2018).
- Plasticity of CD4+ T cell subsets in health and disease (for overview: Kleinewietfeld et al., Semin Immunol. 2013 & Immunol Rev. 2014).
We are looking for a highly motivated postdoctoral researcher to join our team. He/she will be investigating the immune cell balance and the interplay of genetic and environmental factors and its relation to human disease. The position may also involve oversight/supervision of technicians and/or undergraduate and graduate students.
Our lab is part of the VIB Center for Inflammation Research (IRC). VIB is a life sciences research institute in Flanders, Belgium. With more than 1470 scientists from over 60 countries, we perform basic research into the molecular foundations of life. Hasselt University belongs to the "Transnational University Limburg" (TUL; UHasselt, Belgium and Maastricht University, Netherlands) and is located in the heart of Europe, with cities such as Brussels, Liège, Aachen (Germany) and Maastricht (Netherlands) in close proximity.
The ideal candidate has:
- a PhD and/or MD degree in a relevant field.
- a strong track record and excellent technical skills.
- a strong background and experience in murine animal models of disease and cellular immunology and molecular biology techniques.(Felasa B/C certificate to work with animals is required). Experience with murine and human CD4+ T cells, and experience with experimental autoimmune encephalomyelitis (EAE) or humanized mouse models is a plus.
- excellent communication, teamwork and interpersonal skills.
- fluency in written and spoken English.
How to apply?
- Motivated candidates are asked to apply online.
- Please add a list of publications to your CV, as well as a summary of past research and the contacts of 2 referees.
- Please include your certificate in your online application.