The Molecular Biology of Leukemia laboratory(Prof. Jan Cools, VIB - KU Leuven) is looking for a motivated postdoctoral researcher for studies of transcriptional regulation in leukemia.
The project will focus on (i) the study of transcriptional complexes by ChIP-seq and Mass Spec analysis; (ii) the effect on transcription by other mutations; (iii) the use of leukemia mouse models to verify the relevance of these findings.
This position is open to both junior and experienced scientists. We look for highly motivated candidates with an interest in leukemia research and with a track record in cell biology, transcription factor function and/or mouse models. We provide a stimulating and strong scientific environment in a cancer department.
Further info on
- PhD in biology, biochemistry, biotechnology or equivalent
- Strong expertise in basic research technologies (Western blotting, PCR, cloning, cell culture, flow cytometry, etc.)
- Good publication record and strong communication skills in English
- Experience with transcription factors, ChIP-seq, RNA-seq, etc. is a plus
- Experience with mouse cancer/leukemia models is a plus
VIB-KULeuven is an exciting, interdisciplinary research institute with excellent facilities and strong research groups in genetics, oncology, neurobiology, immunology, virology, molecular biology and translational research.
The laboratory of Prof. Jan Cools is located on the Gasthuisberg campus of the KU Leuven (Faculty of Medicine, Center for Human Genetics) and has on-site mouse facilities, sequence facilities and access to leukemia samples.
- Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia.Vanden Bempt M, Demeyer S, et al. Cancer Cell. 2018.
- HOXA9 cooperates with activated JAK/STAT signaling to drive leukemia development. de Bock CE, et al. Cancer Discov. 2018.
How to apply ?
Motivated candidates are asked to apply online. For more information contact Jan Cools.