Postdoctoral scientist in structural biology

Ghent VIB-UGent Center for Inflammation Research

02 Jul 2019

Ghent

VIB-UGent Center for Inflammation Research

Savvas Savvides Lab

Post-doctoral

1

Job description – Her / his Job

We are looking for an enthusiastic and motivated postdoctoral fellow in the Unit for Structural Biology at the VIB-UGent Center for Inflammation Research in Ghent, Belgium. Our group employs an integrative structural biology approach in conjunction with molecular interaction studies and cellular interrogation of the systems under study to elucidate the structural and mechanistic principles underlying the assembly, activation and pathophysiology of macromolecular complexes pivotal to inflammation, immunity, and cancer. 

Recent work by our group includes:

https://doi.org/10.1038/s41586-0191095-5 (Nature, 2019)

https://doi.org/10.1126/science.aaw4295 (Science, 2019)

https://doi.org/10.1016/j.immuni.2017.12.008 (Immunity, 2018)

https://doi.org/10.1038/ncomms14937 (Nature Communications, 2017)

The VIB Center for Inflammation Research offers a very stimulating environment to conduct high-level basic and translational biomedical research supported by an international research community. More information can be found on the following web pages: research department, the VIB, and Ghent University.

Profile

  • PhD in the field of Biochemistry, Biotechnology, Biophysics 
  • Keen interest in structural biology, in particular cytokine-receptor complexes 
  • Broad practical experience in molecular biology, protein biochemistry, and production and purification of recombinant proteins and complexes thereof towards structural and biophysical studies 
  • Research experience in one or several of the following methodological approaches in structural biology is an asset:
    • Single-particle Electron Microscopy
    • Macromolecular X-ray Crystallography
    • Small-angle X-ray Scattering
  • Experience in biophysical methods for the study of protein-protein and protein-ligand interactions (e.g. Isothermal Titration Calorimetry, Surface Plasmon Resonance, Biolayer Interferometry, Multi-Angle Laser Light Scattering)
  • Publication record in international journals subjected to peer-review
  • Collaborative spirit
  • Interest in translational aspects of fundamental research

Essential

  • PhD in the field of Biochemistry, Biotechnology, Biophysics 
  • Proficient in written and spoken English
  • Experience in molecular biology and protein biochemistry
  • Team player, pro-active, good communication skills.

We offer

  • A funded postdoctoral position in structural biology (up to 3 years). The position is available immediately.
  • An opportunity to conduct high-level basic and translational biomedical research supported by an international research community.
  • A stimulating, research environment where quality, professionalism and team spirit are encouraged
  • A versatile and challenging job with very diverse interactions in a world-class research environment, and various opportunities to broaden your expertise.
  • Excellent training in both technical and career skills.
  • A creative and collaborative environment with access to state-of-the-art facilities in the institute

How to apply? 

Motivated candidates are asked to apply online.

Please include a detailed CV with a list of publications, a letter of motivation, and the names of two references. The deadline for application is August, 1st

Informal inquiries to Kenneth Verstraete are welcome.