About the lab
The SWITCH Laboratory is one of the leading laboratories in human disease-related protein aggregation. It is an interdisciplinary workplace, bringing together about twenty researchers from different backgrounds, such as bioinformatics, biophysics and cell biology. SWITCH has a unique platform of technologies for studying protein aggregation, including biophysical, ultrastructural and cell biological instrumentations.
For a primer on who we are, what we do and our latest publications, see http://www.switchlab.org/.
You will investigate the cellular mechanisms and consequences of the interactions of protein aggregates with other cellular proteins. You will work in the context of a bigger project on the specificity of protein aggregation. We have developed a structural hypothesis based on the concept of co-aggregation and have a pipeline in place to identify potential interacting proteins using bioinformatics, biophysical methods and cellular screening approaches.
- PhD in the cell biology of protein aggregation (molecular, cellular, small animal models) or related disciplines
- Strong interest in protein aggregation and its role in disease.
- A solid publication record with first-author research publication(s) in peer-reviewed international journals
- Strong expertise in cloning, genome editing, viral expression
- Strong experience with microscopy and investigating cellular mechanisms
- Highly motivated, enthusiastic, critical and creative
- The ability to work in a multidisciplinary team is a must
- Prior experience with high content analysis is a plus
- A versatile and challenging job
- A vibrant, world-class research environment operating at an international level
- Access to the resources of two host institutions:
- State of the art research facilities
- A dedicated training program to broaden your expertise and enhance your skillset
- A competitive compensation package based on expertise and experience
- Financial support for at least 1 year. The successful candidate is encouraged to obtain a personal fellowship (Marie-Curie, HFSP, EMBO, or national funding organizations)
Starting Date: as soon as possible
How to apply?
For more information contact firstname.lastname@example.org. Please complete the online application procedure and include a detailed CV including list of publications, a motivation letter, and the contact information of three referees.