Postdoctoral Position on polygenic risk, microglia and Alzheimer’s disease

Leuven VIB-KU Leuven Center for Brain & Disease Research

22 Sep 2020

Leuven

VIB-KU Leuven Center for Brain & Disease Research

Bart De Strooper Lab

Post-doctoral

1

Description

The Laboratory for the Research of Neurodegenerative Diseases headed by prof. Bart De Strooper is a vibrant environment where key issues related to Alzheimer’s disease are tackled. We are currently looking for a highly skilled and motivated postdoc to join our multidisciplinary project on polygenic risk scores, Alzheimer’s disease and neuroinflammation (see Sierksma et al. 2020 EMBO Mol Med; Escott-Price et al. 2017 Ann Neurol). 

In this project, we will assess how new insights from the genetics of Alzheimer’s disease, including polygenic risk, can aid in understanding the molecular and cellular basis for Alzheimer etiopathogenesis. The candidate will use human iPS cells both in vitro and in vivo using xenografted mouse models of Alzheimer’s disease (see Mancuso et al. 2019 Nat Neurosci) to gain further insight.

Profile

Required

  • Strong background and hands-on experience with microglia biology and/or stem cell technology
  • Experience with laboratory mice
  • Critical mindset, fast learner & team player
  • Ability to collaboratively lead a multidisciplinary project with international and national partners in academia, industry and the clinics
  • Project management and effective communication skills
  • Good mastery of English language

Appreciated

  • Knowledge on the genetics of Alzheimer’s disease

We offer

  • An exceptionally strong scientific environment
  • Access to state-of-the-art infrastructure
  • A stimulating, diverse, international research environment in a world-class academic laboratory with a focus on Alzheimer’s disease
  • Financial support is available for at least 2 year. However, the successful candidate is encouraged to obtain a personal fellowship (Marie-Curie, HFSP, EMBO, or National funding organizations).

Start date: as soon as possible - the position is available immediately

How to apply?

Please complete the online application procedure and include a detailed CV, a motivation letter describing research interests and previous research experience and a list of publications.

For more information: please contact annerieke.sierksma@kuleuven.vib.be.