PhD Position in the study of microglial biology and neuroimmunology in Alzheimer’s disease

Antwerp VIB-UAntwerp Center for Molecular Neurology

14 Jul 2020

Antwerp

VIB-UAntwerp Center for Molecular Neurology

Renzo Mancuso Lab

PhD

1

Description

The laboratory of Microglia and Inflammation in Neurological Diseases (MIND), headed by Renzo Mancuso, is a part of the VIB-Center for Molecular Neurology (CMN) and focuses on multiple aspects of microglial biology and neuroinflammation in Alzheimer’s disease and other brain disorders.

This is an exciting job opportunity that aims to elucidate the role of microglia in Alzheimer’s disease. Recent genetic findings place microglia as central transducer of genetic risk for Alzheimer’s and you will investigate how translates into microglial functional alterations and leads to pathology. The applicant will be at the interface of cutting-edge research using stem cell technology and state-of-the-art humanized microglia mouse models, Alzheimer’s disease genetics and translation towards novel therapies.

Selected references:

  • Mancuso R et al. Nat Neurosci 2019, 22:2111-2116.
  • Mancuso R et al. Brain 2019, 142:3243-3264.

Profile

We are looking for a motivated researcher with an interest in neuroimmunology and neurodegeneration. This position is open to candidates that have:

  • Master degree in neuroscience, molecular biology, cell biology, biochemistry, biomedicine or related disciplines
  • Proficient verbal and written English communication skills.
  • Knowledge in bioinformatics or experience with iPSC cultures would be an advantage
  • Ability to summarize data extracted from literature and to define research objectives.
  • Passion for science, self-motivation, flexibility and team spirit.

We offer

We offer a full 1-year contract extendable, to work in an enthusiastic and dynamic scientific environment. During this time, you will be encouraged to apply for national and international PhD scholarships.

As part of the VIB-UAntwerp Center for Molecular Neurology and VIB, the applicant will benefit from established collaborations and access to centralized facilities with expertise in genomics, functional genomics and cell biology, proteomics, cutting-edge microscopy, structural biology, technology development, and bioinformatics.

VIB provides a highly interactive environment and ample training opportunities for its researchers. In addition, the VIB-UAntwerp Center for Molecular Neurology is located in the city of Antwerp, the capital of Flanders, offering a culturally and historically rich, and ethnically diverse environment.

Starting date: as soon as possible

How to apply?

Please complete the online application procedure and include a detailed CV, a motivation letter describing research interests and contact details of 1-2 referees.

For more information: please contact renzo.mancuso@uantwerpen.vib.be