Computational biology researcher to investigate Alzheimer’s disease

Leuven VIB-KU Leuven Center for Brain & Disease Research

23 Feb 2021

Leuven

VIB-KU Leuven Center for Brain & Disease Research

Bart De Strooper Lab

Post-doctoral

1

Computational biology researcher to investigate Alzheimer’s disease using spatial transcriptomics in preparation of a new spin-off company K5

Description

The Laboratory for the Research of Neurodegenerative Diseases headed by prof. Bart De Strooper is a vibrant environment where key issues related to Alzheimer’s disease are tackled. We are currently looking for a highly skilled and motivated postdoc to join our multidisciplinary project on the cellular response to Alzheimer’s pathology (De Strooper and Karran, Cell, 2016). 

In this project, we will use spatial transcriptomics (Chen and Lu, Cell, 2020) to investigate why some people remain protected against Alzheimer’s Disease despite the presence of amyloid plaques. Understanding resilience to Alzheimer’s disease will help us to identify new drug targets. The candidate will closely collaborate on data analysis, interpretation and identification of novel drug targets for Alzheimer’s Disease, together with the wider team of biologists and bioinformaticians. The candidate will be responsible for the data analysis part of the company and will have the possibility to step into the company.

Profile

Required

  • Ph.D. in computational biology, biomedicine, genetics or equivalent
  • Strong background in computational biology and data analysis
  • Strong background in spatial or single-cell omics applications
  • Strong background or interest in drug discovery and development
  • Strong interest in brain pathology and Alzheimer’s Disease
  • Critical mindset, fast learner & team player
  • Ability to collaboratively lead a multidisciplinary project with international and national partners in academia, industry and the clinics
  • Project management and effective communication skills
  • Good mastery of the English language

Appreciated

  • Experience with image analysis and/or statistics
  • Knowledge of the genetics of Alzheimer’s disease

We offer

  • A stimulating, diverse, international and exceptionally strong research environment in a world-class academic laboratory with a focus on Alzheimer’s disease
  • Opportunity to learn state of the art technology
  • Opportunity to work with an excellent bioinformatics team
  • Access to state-of-the-art infrastructure
  • The candidate will have the opportunity to join the spin-off company at the end of 2021.

Start date: as soon as possible - the position is available immediately.

How to apply?

Please complete the online application procedure and include a detailed CV, a motivation letter describing research interests and previous research experience and a list of publications.

For more information: please contact mark.fiers@kuleuven.be.