Postdoc Cell Biology of Protein Aggregation

Leuven VIB-KU Leuven Center for Brain & Disease Research

14 Jul 2020


VIB-KU Leuven Center for Brain & Disease Research

Frederic Rousseau and Joost Schymkowitz Lab



About the lab

The SWITCH Laboratory is one of the leading laboratories in human disease-related protein aggregation. It is an interdisciplinary workplace, bringing together about twenty researchers from different backgrounds, such as bioinformatics, biophysics and cell biology. SWITCH has a unique platform of technologies for studying protein aggregation, including biophysical, ultrastructural and cell biological instrumentations.

For a primer on who we are, what we do and our latest publications, see

Your Job

You will investigate the cellular mechanisms and consequences of the interactions of protein aggregates with other cellular proteins. You will work in the context of a bigger project on the specificity of protein aggregation. We have developed a structural hypothesis based on the concept of co-aggregation and have a pipeline in place to identify potential interacting proteins using bioinformatics, biophysical methods and cellular screening approaches.


  • PhD in the cell biology of protein aggregation (molecular, cellular, small animal models) or related disciplines
  • Strong interest in protein aggregation and its role in disease.
  • A solid publication record with first-author research publication(s) in peer-reviewed international journals
  • Strong expertise in cloning, genome editing, viral expression
  • Strong experience with microscopy and investigating cellular mechanisms
  • Highly motivated, enthusiastic, critical and creative
  • The ability to work in a multidisciplinary team is a must
  • Prior experience with high content analysis is a plus

We offer

  • A versatile and challenging job
  • A vibrant, world-class research environment operating at an international level
  • Access to the resources of two host institutions:
    • VIB, an excellence-based research institute
    • KU Leuven, one of Europe‚Äôs leading research universities 
  • State of the art research facilities
  • A dedicated training program to broaden your expertise and enhance your skillset
  • A competitive compensation package based on expertise and experience
  • Financial support for at least 1 year. The successful candidate is encouraged to obtain a personal fellowship (Marie-Curie, HFSP, EMBO, or national funding organizations)

Starting Date: as soon as possible

How to apply?

For more information contact Please complete the online application procedure and include a detailed CV including list of publications, a motivation letter, and the contact information of three referees.