Postdoc Cell Biology of Protein Aggregation

Leuven VIB-KU Leuven Center for Brain & Disease Research

14 Jul 2020

Leuven

VIB-KU Leuven Center for Brain & Disease Research

Frederic Rousseau and Joost Schymkowitz Lab

Post-doctoral

1

About the lab

The SWITCH Laboratory is one of the leading laboratories in human disease-related protein aggregation. It is an interdisciplinary workplace, bringing together about twenty researchers from different backgrounds, such as bioinformatics, biophysics and cell biology. SWITCH has a unique platform of technologies for studying protein aggregation, including biophysical, ultrastructural and cell biological instrumentations.

For a primer on who we are, what we do and our latest publications, see http://www.switchlab.org/.

Your Job

You will investigate the cellular mechanisms and consequences of the interactions of protein aggregates with other cellular proteins. You will work in the context of a bigger project on the specificity of protein aggregation. We have developed a structural hypothesis based on the concept of co-aggregation and have a pipeline in place to identify potential interacting proteins using bioinformatics, biophysical methods and cellular screening approaches.

Profile

  • PhD in the cell biology of protein aggregation (molecular, cellular, small animal models) or related disciplines
  • Strong interest in protein aggregation and its role in disease.
  • A solid publication record with first-author research publication(s) in peer-reviewed international journals
  • Strong expertise in cloning, genome editing, viral expression
  • Strong experience with microscopy and investigating cellular mechanisms
  • Highly motivated, enthusiastic, critical and creative
  • The ability to work in a multidisciplinary team is a must
  • Prior experience with high content analysis is a plus

We offer

  • A versatile and challenging job
  • A vibrant, world-class research environment operating at an international level
  • Access to the resources of two host institutions:
    • VIB, an excellence-based research institute
    • KU Leuven, one of Europe‚Äôs leading research universities 
  • State of the art research facilities
  • A dedicated training program to broaden your expertise and enhance your skillset
  • A competitive compensation package based on expertise and experience
  • Financial support for at least 1 year. The successful candidate is encouraged to obtain a personal fellowship (Marie-Curie, HFSP, EMBO, or national funding organizations)

Starting Date: as soon as possible

How to apply?

For more information contact  hannah.wilkinson@kuleuven.vib.be. Please complete the online application procedure and include a detailed CV including list of publications, a motivation letter, and the contact information of three referees.