Mitochondrial Metabolism, cell death and intratumor microbiome
Do you want to join @FendtLab for your Postdoctoral Research?
We (Laboratory for Cellular Metabolism and Metabolic Regulation; Fendt Lab) are a young and dynamic team of researchers performing cutting-edge cancer metabolism research with special focus on cancer metastasis, novel metabolic pathways and aim to broaden our research to the role of intratumor microbiome in cancer metabolism and cancer progression. We exploit mouse models, genetic engineering, metabolomics and single-cell & spatial multi-omics analysis to gain groundbreaking insights into metabolism as a driving force of cancer progression. Our work is published in high-profile journals such as Nature, Nature Cancer, Cell Reports, and Molecular Cell. We have strong international recognition and top collaboration partners all over the world.
The VIB-KULeuven Center for Cancer Biology (CCB), located on Campus Gasthuisberg of the University of Leuven, contributes to the better understanding of the biology that underlies cancer initiation, progression and metastatic dissemination with the ultimate goal of developing more effective and specific anti-cancer (combination) therapies. CCB is currently composed of more than 200 scientists in 13 independent research groups and units. Our scientific interest lies in various hallmarks of tumors and their microenvironment, including inflammation, metabolism, genetic and epigenetic regulating circuits. CCB fosters an interdisciplinary environment and close collaboration with the Comprehensive Cancer Center LKI and the University Hospital, both located on the same campus, to promote translational research.
VIB is an entrepreneurial and vibrant non-profit research institute in Flanders-Belgium with a clear focus on groundbreaking research in life sciences. About 1500 scientists and technologists from over 60 countries are based at the 5 Flemish Universities of Ghent, Leuven, Antwerp, Brussels and Hasselt, and are studying the broad spectrum of molecular mechanisms that regulate the functions of the human body, plants and microorganisms.
Are you interested in mitochondrial metabolism and the role of intratumor microbiome in cancer metastasis? You have a strong background (PhD) in mitochondrial metabolism, cell death and/or intratumor microbiome. Having successfully applied state-of-the-art genetic engineering technologies (such as CRISPR/Cas9), molecular biology techniques including but not limited to western blot, qPCR, FACS, immunohistochemistry (IHC), confocal microscopy, microbial analysis and cell culture techniques is a plus. You are interested in metabolism and metastasis research. You like taking the scientific and experimental lead on a challenging project. You can work independently but also like to collaborate within the team and other research groups. You aim for high impact and are highly ambitious.
- Postdoc position
- Cutting-edge research projects
- The opportunity to lead an exciting research project on metastasis & metabolism
- Multidisciplinary and international collaborations
- Beyond state-of-the-art technologies including (single cell and spatial) multi-omics analyses
- Teamwork and individual research career development
- International team of young and dynamic researchers
Start date: 2024
How to apply?
Please apply to [email protected]: a motivation letter, full CV, list of publications, and contact details of 3 referees in one single PDF file.
For more information:
Leuven - only 20 minutes away from Brussels by train - is a vivid university city with a rich history, a well-preserved historical town center and a lively multi-cultural atmosphere. The city is surrounded by charming small villages, woods and nature. Leuven has a lively atmosphere because of the many students from all over the world.
Leuven is home to KU Leuven, the largest and oldest university of the Low Countries and one of the oldest universities in Europe. The related university hospital of UZ Leuven is one of the largest hospitals in Europe.
Leuven and the surroundings are a great place for young people and families to live and raise children. There are many excellent day care centers and schools including an international school.